Tuesday, February 25, 2014

A Bright Sunshiny Day!

It was a beautiful sunny day today, with no rain!

We went to the clinic today and learned that we still have more to learn. That's often the way it is around here, so we shouldn't be too surprised. 

The bone marrow results are back and tell us a bit of a story ...,  Here is what we learned.  I know it is confusing and I apologize, but I do want to record it.

Chimersism Whole Bone Marrow (Whole means they did not separate the CD3, CD33,and CD56 cells) on 2/20/14 =
42% donor 2 (12/24/2013 was 60%)
5% donor 1  (12/24/2013 was 4%)
53% host   (12/24/2013 was 36%)

Chimerisms CD3+  T cells / lymphocytes on 2/20/14 = 26%  donor 2  
(1/7/14 was 30%, 12/24/13 was 19%)

Chimerism CD33+  myeloid cells / neutrophils  on 2/20/13 = 84% donor 2 
(1/7/14 was 95%, 12/24/13 was 90%)


Flow cytometry on 2/20/14 tell us that the myleloid cells increased from 8% to 9.8% since 1/28/14. 

Oh Bother!   It's obvious that the trend is the wrong direction in every cell count.

So what does all this mean?  That was our question.  What next?


They suggest Terry continue with the Vidaza.  A total of 6 are suggested and he has had 2 already.  The next one is due to begin next week.  However, this could be done in Wenatchee, so it's possible we could be going home as early as next week. 
BUT,
They are still discussing the option of a DLI (donor lymphocyte infusion), which would mean we need to stay here for that.  If they do a DLI it could possibly be done next week and we will have to stay another couple weeks after that to watch for GVHD. 

They will contact us when a decision is made.

We'll let you know ...



1 comment:

Bonnie said...

Winnie the Pooh is right, "oh bother!" Prayers continue.